NEW YORK --A new study by researchers at New York University School of Public Health (NHS), shows that over two decades, Americans taking a new anti-inflammatory drug, called Celebrex, had an increased risk of heart disease.
A recent study of 1,500 adults found that patients taking the drug had a 30 percent higher risk of dying than those who did not take the drug. Researchers also found that people taking the drug had a 40 percent higher risk of dying from cancer, diabetes, heart disease, lung disease and stroke.
"People who are diagnosed with heart disease, especially the elderly, are at increased risk of dying from heart disease, cancer, diabetes and stroke," said study leader Dr. Joseph Farias, M. D., professor of medicine at the University of California, San Francisco. "This may be due to a combination of factors, such as age, smoking, obesity and disease burden."
The findings are published in the journal U. S. medical journal, Heart Disease. It's a follow-up of a previous study of about 1,000 patients in an in the previous year, and showed that those on the drug had a 20 percent higher risk of dying from heart disease.
Celebrex is an anti-inflammatory drug used to treat arthritis, muscle pain and inflammation. It belongs to the class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs), which work by reducing the production of hormones that cause inflammation.
It's also used to treat other types of pain. Celebrex is used to reduce pain, inflammation, swelling and stiffness, and may also be used to treat menstrual pain.
The new study was led by Dr. Farias, M. D., and colleagues at the University of California, San Francisco.
"In the vast majority of patients who took these drugs, they had a 40 percent higher risk of dying from heart disease than those who did not take the drug," said Dr. "It's important to remember that the risk for heart disease has been associated with taking a lower dose of NSAID drugs and the drug's side effects."
About 2 million Americans have heart disease, according to the National Heart, Lung and Blood Institute, a group of doctors and researchers who work with the health care system. The National Institutes of Health is an insurer of the American Heart Association.
In a, researchers found that patients taking a drug for heart disease had an increased risk of a "serious, possibly fatal, adverse event." A similar risk was found in those taking the drug for cancer.
Researchers also found that people taking the drug had a 20 percent higher risk of dying from cancer, diabetes, heart disease and stroke. They also found that people taking the drug had a 40 percent higher risk of dying from lung disease, diabetes and heart disease.
The results were published in the journal's journal,JAMA Internal Medicine.
"The results are an important first step in the development of effective medicines to treat chronic diseases and other health problems," said Farias. "The findings were supported by a large population-based study of patients with heart disease who were followed for six months and then again for the next six months. We hope that these new data will help us better understand the risks and benefits of taking a new medication."
Dr. D., who is also a professor of medicine at the University of California, San Francisco, says that the new findings are important because the drug is not FDA-approved for any other use. But he also noted that the new study only found a 40 percent increased risk of dying from heart disease.
The new study is the largest since the previous study began five years ago, which showed that Celebrex was not associated with a higher risk of cardiovascular death or heart attack in a population of more than 1,000 people. The new study is the latest work on the safety and efficacy of Celebrex to study its cardiovascular risks.
The new study was funded by AstraZeneca Pharmaceuticals LP, a San Diego-based drug company that makes Celebrex.
Farias said the new study found that people taking the drug had a 40 percent higher risk of dying from heart disease than those who did not take the drug. It was also found that those taking the drug had a 40 percent higher risk of dying from lung disease, diabetes and heart disease.
CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).
CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).
CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).
The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).
Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).
CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.
CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.
How should I take CELEBREX 200MG CAPSULE?The usual dose was 200 mg once daily for a period of 3 days, to be taken at the same time each day and no more than once a day. Swallow the medicine with a glass of water with at least four separateuddies. Do not crush or chew the medicine.
You should not take more than one dose of CELEBREX 200MG CAPSULE a day, it is suggested to take it at a time.
If you take more than the recommended dose of CELEBREX 200MG CAPSULE, you may experience joint pain, swollen hands and feet, dark urine, abdominal pain, shortness of breath, nausea and dizziness.
ICE ( infection and0.5% cream) recommendedongees: clean and dry the affected area, and wait for 15-20 minutes while symptoms resolve. Rub CELEBREX 200MG CAPSULE into the affected area for 15-20 minutes. Then wash down the surface with water and continue for another 15-20 minutes. When symptoms return, seek medical attention as symptoms may be lost.
How long does it take for CELEBREX 200MG CAPSULE to work?The duration of action of CELEBREX 200MG CAPSULE is between 1 and 4 hours. See for more details.
The cream should not take long to start working as it is foresian (acerbation of) symptoms of a viral infection like the common cold or the flu.
CELEBREX 200MG CAPSULE is contraindicated in patients with severe liver disease (such as advanced hepatic insufficiency) and/or with etiology of a ulcer in stomach/intestines.
Caution is recommended in patients with mild to moderate pain of moderate pain. It is not recommended for use in combination with other NSAIDs as it may cause serious drug-drug interactions with other medications.
The brand Celebrex is available in capsules of 400 mg each. This medication can be taken once daily or once a day. Celebrex 200 mg is available as a capsule, as a suspension, and as a chewable tablet.
Celebrex 200 mg (the generic name for Celebrex) is used for the treatment of osteoarthritis and ankylosing spondylitis. This medication is not approved for the treatment of pain, as a cure for pain.
Celebrex is used to treat pain and to decrease stiffness.
Celebrex 200 mg is used to relieve the symptoms of arthritis in adults, including the following:
- joint pain that is not relieved by physical activity - stiffness and/or pain - stiffness and/or inflammation - ankylosing spondylitis - ankylosing spondylitis where the inflammation in the synovial space is decreased - pain during sexual intercourse - ankylosing spondylitis where the inflammation is decreased - swelling of the spine - pain in upper back - shortness of breath - difficulty in sleeping - weakness and restlessness - tiredness - stiffness and/or pain - tenderness and/or swelling of the vertebral column - vertebral osteoarthritis - a painful and unstable condition that can affect both the knees and hips.
Celebrex 200 mg is also used to treat pain in the following conditions:
- ankylosing spondylitis - pain during sexual intercourse - pain during sexual intercourse - ankylosing spondylitis - pain during sexual intercourse - pain during intercourse with a heavy meal - arthritis - joint and/or cartilage degeneration - bone and joint disorders - muscle spasm - pain during sleep - weakness and/or restlessness - tiredness - stiffness and/or pain during sleep
Celebrex 200 mg is not for use by the elderly. Your doctor may advise you to take the medicine for a longer time.
Celebrex (celecoxib) is an oral medicine (NSAID) that was developed by the company that makes Celebrex. It works by blocking the production of certain hormones in the body that cause inflammation and pain.
Celebrex is a prescription medication. You must have a valid prescription from a licensed medical professional before you can take Celebrex.
The maximum recommended dose of Celebrex for the treatment of osteoarthritis and ankylosing spondylitis is two 200 mg capsules (800 mg each) taken once daily with a full glass of water.
Celebrex 200 mg is available as a capsule, a suspension, and a chewable tablet.
Celebrex 200 mg is used to relieve the symptoms of arthritis in adults, including the following conditions:
- joint pain that is not relieved by physical activity - stiffness and/or pain - stiffness and/or inflammation - ankylosing spondylitis - ankylosing spondylitis - pain during sexual intercourse - ankylosing spondylitis - pain during sexual intercourse - pain during intercourse with a heavy meal - arthritis - joint and/or cartilage degeneration - bone and joint disorders - muscle spasm - pain during sleep - weakness and/or restlessness - tiredness - stiffness and/or pain during sleep
Celebrex is an anti-inflammatory and analgesic drug that has been found to increase the relief of moderate to severe pain and reduce the risk of osteoarthritis. It is also approved for the treatment of arthritis and pain in adults.
Celebrex is used to treat osteoarthritis of the knees, hips, and shoulders.
This is a list of medications, including all prescription and over-the-counter medicines, that patients can order online from Canada Drugs Direct.
The list includes prescription and over-the-counter medicines. They can be purchased on Canada Drugs Direct.
This list is based on theCanada Drugs Direct Health Insurance Policy (
).
What is the most important medicine that is aprescription or over-the-counter?
The most important prescription or over-the-counter medicine in Canadais, which is one of the medicines that patients have to take. If you are prescribed a medicine, you have to talk to your doctor about it and get your prescription or over-the-counter medicine.
What are the different kinds of medicines that can be prescribed to patients?Here’s what you should know about each medicine:
1. COX-2 inhibitors:These include:
The second type of medicine is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs are available as capsules or tablets. You have to take it twice a day with each dose. The dose will be taken at the same time each day, and there will be a gap of about 2 weeks. Your doctor will talk with you about your treatment plan, so you can take your medicine in the normal dose for the shortest possible time.
These medicines are available on Canada Drugs Direct.
What are the different types of medicines that are notprescribed or over-the-counter?
2.
3.
4. Celecoxib:
5.
6.
The best way to save on prescription pain medication is to get it from a reputable pharmacy.
If your insurance doesn’t cover prescription medication for your condition, you might be surprised to learn that Celebrex (celecoxib) is a popular over-the-counter medication.
This is especially true for people who take prescription painkillers to manage moderate to severe pain. Celebrex helps to relax blood vessels and increase blood flow to the heart, reducing heart attack and stroke.
It’s important to understand that Celebrex doesn’t work as advertised, and its side effects aren’t dangerous. However, the drug may have harmful effects on other parts of the body, so it’s important to consult with a healthcare professional before using it.
If you’re unsure about whether you should take Celebrex, here’s a list of the common side effects of Celebrex:
If you’re concerned about Celebrex side effects, talk to your doctor. They can assess your suitability for the drug and suggest other options.
For further information about Celebrex, visit the Celebrex site on the National Institutes of Health.